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And then what's important here is this analysis where glucose control which is really you know, how well the diabetes is controlled in patients.
这里很重要的一点是为了控制葡萄糖如果II型糖尿病患者要控制糖尿病
Who have Type 2 diabetes and take 1, 2, 3 drugs what is the impact of having OSA so it is compared to not having OSA.
他们需要服用1种 2种3种药物那么睡眠性呼吸障碍有哪些影响呢因此我们将其与没有睡眠性呼吸障碍
Having even mild OSA is associated with an increase in hemoglobin A1C of 1% I can tell you to get a decrease of 1% in your hemoglobin A1C.
中度睡眠性呼吸障碍进行了比较他们的血红蛋白A1c会增加1%如果你患有糖尿病
If you are diabetic you have to take at least one drug and having severe OSA.
如果想让血红蛋白Aic降低1%你至少要服用一种药物然后严重的睡眠性呼吸障碍的对象
Is compared to no OSA is associated with an increase in hemoglobin A1C by 2% which is really the equivalent of 2 to 3 drugs.
与无睡眠性呼吸障碍的对象进行了比较发现他们的血红蛋白A1c升高了2%那么需要服用2到3种药物才能达到这个效果
Now this is a cross-sectional analysis it doesn't have...doesn't tell us about the direction of causality.
这也是一个横断面研究并没有告诉我们因果关系的发展方向
And clearly the major questions are whether effective treatment of OSA can improve glycemic control in patients with Type 2 diabetes.
显然 主要的问题是对睡眠性呼吸障碍的有效治疗能够改变II型糖尿病患者的血糖
The data so far even though quite a number of groups are working on this remain somewhat inconclusive.
目前的数据显示尽管有很多研究团队致力于这个问题的研究但这个问题的答案还不确定
Not terribly encouraging one issue of course is compliance which is generally low.
而且也不是那么鼓舞人心当然其中一个问题是患者的依从性还比较低
And the second question would be does effective treatment of OSA if we had a treatment.
第二个问题是对睡眠性呼吸障碍的有效治疗如果我们确实有治疗方法
To which the subject would be really compliant would it delay the development of Type 2 diabetes or reduce the severity.
而且试验对象也比较依从那么这种方法能否减缓II型糖尿病的发展或是减轻其严重程度?
And with these thoughts I will thank the numerous people who are working in this area with me.
我把这些问题留给大家我想感谢在这个领域和我共事的这些研究人员
