lose one's mind的意思是抓狂、发疯、失去理智,常见的有lose my mind,lose your mind等等.
Taking a child on a motorbike without a helmet! Have you completely lost your mind?
骑摩托车带孩子却不带头盔,你是不是疯了?
Do you lose your mind? You want to marry that guy?
你一定是昏了头吧?你想嫁给那个家伙?
The stress of this movie is making me feel like i'm losing my mind.
这部电影给我的压力使我抓狂.
He was not the only prisoner to lose his mind.
他不是唯一一个失去理智的囚犯.