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A diet supplemented with soy protein may ease the severity of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, according to American research carried out on mice and cultured human colon cells. The news comes ahead of World Inflammatory Bowel Disease Day, May 19.
据美国开展的一项基于老鼠和人工培养的人类结肠细胞的研究表示：一份补充大豆蛋白的饮食或能缓解炎症性肠道疾病病情，比如克罗恩病和溃疡性结肠炎。这一消息发生在5月19日世界炎症性肠道疾病日之前。
Researchers at Penn State University in the USA found that soy protein concentrate had an antioxidant and cytoprotective effect in cultured human bowel cells and moderated the severity of inflammation in mice with induced inflammatory bowel disease.
美国宾夕法尼亚州立大学的研究人员发现：大豆蛋白浓缩物在人工培养的人肠细胞中含一种抗氧化剂，并有保护细胞的作用，能缓和患有炎症性肠道疾病的小鼠的炎症程度。
Crohn's disease and ulcerative colitis are two forms of inflammatory bowel disease (IBD), characterized by chronic inflammation of all or part of the digestive tract, generally the intestine, the colon and the rectum. Symptoms include abdominal pain, diarrhea, fatigue, appetite loss and weight loss.
克罗恩病和溃疡性结肠炎是两种不同的炎症性肠道疾病，其特征是全部或部分消化道，通常为肠、结肠和直肠的慢性炎症。症状包括腹痛、腹泻、疲劳、没胃口和体重下降。
Mice with an induced condition similar to ulcerative colitis were given a dietary soy protein concentrate (12%). An equivalent amount of other forms of protein was removed from their diet to replicate a more human-relevant scenario. Both body weight loss and swelling of the spleen improved in the mice. What's more, the scientists observed reduced inflammation in the colon and improved gut barrier function.
研究员给患有类似于溃疡性结肠炎的老鼠提供了大豆蛋白浓缩物（12%浓度）饮食。同时不再提供等量的其它形式的蛋白，以复制更人性化的场景。老鼠的体重下降和脾脏肿胀症状均有改善。此外，科学家们还观察到了结肠炎症有所减轻，肠屏障功能也有所改善。
The researchers consider that the inflammation-moderating effects may be linked to soy protein, but not solely. In fact, the soy protein concentrate contains 70% protein as well as some soy fiber, which could also have a beneficial effect on the digestive system. The scientists plan further studies to investigate.
研究员认为炎症缓解可能与大豆蛋白有关，但却不限于此。事实上，大豆蛋白浓缩物含有70%的蛋白及一些大豆纤维，有益于消化系统。科学家计划进一步研究调查。
Four million people worldwide suffer from IBD. Both Crohn's disease and ulcerative colitis are treated with anti-inflammatory or immunomodulatory therapies or by surgery in severe cases. World Inflammatory Bowel Disease Day is May 19, 2017. The study is published in the Journal of Nutritional Biochemistry.
全世界有400万人患有炎症性肠道疾病。人们通常用抗炎或免疫调节疗法治疗克罗恩病和溃疡性结肠炎，严重情况下，还会动手术。2017年世界炎症性肠道疾病日为5月19日。该研究发表在《营养生物化学》期刊上（the Journal of Nutritional Biochemistry）。
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