The Food and Drug Administration just issued a special announcement about a new health risk that they worry may be linked to e-cigarettes: seizures.
美国食品药品监管局刚刚发布一则特殊声明：他们担心电子烟或导致新的健康风险--癫痫。
Since June 2018, the agency received what it called "a recent uptick" in reports where users describe having seizures that may be connected with their e-cigarette use. The FDA collects information about vape safety risks through their Safety Reporting Portal, where people who use e-cigarettes can share their experiences. Between reports via that portal and from poison control centers, the FDA counted 35 reports of seizures between 2010 and early 2019 that may be related to vaping. Most of those, it said, involved "youth or young adult users."
自2018年6月以来，该机构收到了其所谓的"近期上升"报告。报告指出，电子烟用户称他们癫痫发作或与抽电子烟相关。美国食品药品监管局通过其安全报告通道收集了关于电子烟安全风险的信息，电子烟用户会通过安全报告通道分享个人经历。透过来自安全报告通道的报告及中毒控制中心的报告，美国食品药品监管局发现，自2010年至2019年初，共计35份癫痫报告与电子烟相关。其中，大多数报告表示，涉及了"青少年或年轻成人用户。"
We know that nicotine poisoning can cause seizures, like when people swallow vape juice. But the FDA doesn't know yet what the relationship between seizures and vaping is here, says FDA Commissioner Scott Gottlieb in a statement today. Some of these seizures might be unconnected, or some might be caused by inhaling massive amounts nicotine. That seems less plausible, says Peter Chai, a medical toxicologist at Brigham and Women's Hospital in Boston. "I think exposure (skin contact or oral) in children, or vaping exposure in younger individuals (adolescents through which we've seen a large increase in e-cig use), might be accounting or the increase in these seizures," he says in an email to The Verge.
我们知道，尼古丁中毒会导致癫痫，就像喝烟油一样。但美国食品药品监管局并不清楚癫痫与电子烟之间的关系，美国食品药品监管局局长斯科特·戈特利布在今日发布的声明中说道。有些癫痫发作与吸入大量尼古丁无关，而有些则正是因为吸入大量尼古丁引起的。波士顿布莱根妇女医院（Brigham and Women's Hospital）的医学毒理学家彼得·柴说，这似乎是不合理的。"我认为儿童接触（皮肤或口腔接触），或年轻人接触电子烟（青少年--吸电子烟的青少年越来越多），可能是导致癫痫发作的原因，"他在发给The Verge杂志的一封邮件中写道。
"To get enough nicotine in your body to cause seizures by smoking cigarettes is well-nigh impossible," says medical toxicologist Edward W. Boyer, an associate professor of emergency medicine at Brigham and Women's Hospital. But similar cases of nicotine-related seizures have been linked to eating it. Boyer thinks it's plausible that e-cigarettes could deliver enough nicotine to do the same. The truth is, there's not much data to go on. And for now, the FDA's Gottlieb says, "We can't yet say for certain that e-cigarettes are causing these seizures."
"通过吸烟使体内有足够的尼古丁引发癫痫几乎是不可能的，"布莱根妇女医院的紧急医学副教授、医学毒理学家爱德华·博耶尔说道。但与尼古丁相关的癫痫发作的类似病例与摄入尼古丁相关。博耶尔认为电子烟无法带来如此量大的尼古丁。事实是，可供继续研究的数据并不多。就目前而言，美国食品药品监管局局长戈特利布说道，"我们尚不能确定，电子烟会导致癫痫发作。"
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