So I'm gonna talk about the role of sleep deficiency
所以我打算讲讲睡眠缺乏
in predisposing to obesity
在肥胖症易感性
and in that way to chronic health conditions across your lifespan
以及一生中所患慢性疾病中起到了什么作用
Then I'll touch on some mechanisms
然后我还会简单讲讲这中间的机制
I'll talk about some of our sort of real life data
讲讲对青少年饮食和睡眠不足问题进行了研究后
on diet and sleep deprivation in teens
我们得到了哪些现实数据
I'm going to identify some paradoxes
我还要澄清一些矛盾
that I've seen in literature and certainly in our own data
很多研究文献 当然也包括我们自己的研究
about age and gender
对年龄和性别差异都存在一些矛盾
and maybe challenge you to think about what
我还想让大家思考
if they are real
如果这些矛盾确实存在
what they may be informing us
那么它们在生物学和发生机制上
about biology and mechanism
对我们有什么启示
Then I'm going to also talk a little bit
接下来 我还要简单讲讲
about some of the childhood risk factors
童年时期的那些风险因素
that might be a key link between sleep deficiency and obesity
可能成为睡眠缺乏和肥胖症之间的关键连接
So I'd like you to start thinking too
首先 请大家思考
as we think about our lifespan approach
从人的全部生命期来看
is there a developmentally critical period
是否存在一个关键的发展期阶段
where sleep deficiency may be particularly potent as a stimulus for obesity?
在这个阶段中 睡眠缺乏成为了肥胖症最重要的诱因?
Again,
这个问题
this is a little contrasted to our very first session that this morning
和我们今天早上听到的报告刚好相反
we were told like
今天早上的报告告诉我们
let's look at the middle-aged people
看看中年人的情况吧
So many of you know this very old article now
你们很多人都知道这篇早期发表的文章
but what this really shows is
但这篇文章显示
the importance of obesity in childhood about risk
童年时期肥胖的儿童
as a risk fact becoming obese as adults
成年后存在肥胖的风险