And the reason why this nutrient can affect so many different tissues with so many different symptoms to produce this syndrome
维生素D这种营养素能影响如此多的组织,同这么多病症具有联系
that we spoke about is that when vitamin D is in short supply
这是因为维生素D不足时
the various tissues in cells of our bodies can't make the calcitriol. they need to open up the DNA librariesfast or adequately enough
体内各组织细胞无法制造足够的骨化三醇来快速有效地开启DNA信息库
Recall, each molecule gets used only once
记得吧,每个分子只能用一次
If you've got a shortage of the molecules and you don't make as many transcripts of the genes that you need in order to respond
其分子不够的话就无法得到足够转录和应答
So the functioning of the tissue concern is not so much stopped as blunt or impaired
这时组织的功能就会迟钝,受损
So what are the consequences?
结果是什么呢
Well we've seen them all day and we haven't seen all of them. They have been timed
这一天都是讨论这些病症
We have bone diseases, osteoporosis, osteomalacia, rickets
有骨骼疾病,骨质疏松,骨质软化,佝偻病
We have increased falls and fractures. We have high blood pressure and I'll show you some data on that
跌倒更容易骨折,有高血压,我会展示更多数据的
Increased risk of cardiac disease and death prematurity, low birth weight and increased caesareans
心脏病及死亡风险提高,早产,低出生体重,剖腹产增加
Some of which Dr. Wagner spoke about Diabetes and metabolic syndrome, periodontal disease
一些Wagner医生讲过糖尿病,代谢综合症,牙周病
which is one of the interesting outcomes in Dr. Wagner's study
这也是Wagner医生的一个有趣研究
She didn't have a chance to talk about Decreased resistance to infection Various kinds of increased risk of multiple sclerosis
她还没来得及讲抵抗力降低,增加多发性硬化症风险
On and on. I could put more there, but I ran out of room on the slide
等等还有很多,只是幻灯片空间不够了