I'm not sure they were right in demanding it but okay they demanded it
我不确定这样要求是否合理,反正他们是要求了
and we have there well over 30 randomized controlled trials that have evaluated a causal connection between serum 25D and various health benefits
而我们有超过30个的随机对照试验,它们评估了血清25D同健康好处的因果关联
Most of them of course have been in the field of bone disease because we've had the obvious connection between vitamin D and bone for so much longer
大多数都是在骨病领域,维生素D和骨骼的联系毕竟是最古老的课题
but there at least 5 for falls, 2 for hypertension, 1 for cancer, 1 for adjuvant TB therapy, 3 for respiratory infection
还有至少5个关于跌倒,2个关于高血压,1个关于癌症,辅助结核病疗法1个,呼吸道感染3个
not counting whatever you might have had that Dr. Wagner in her pregnancy study
不包括Wagner医生讲的妊娠研究,
1 for pregnancy outcomes. I should count that 2, because there are really two studies there
妊娠结果1个,应该是2个,我记得有2项研究
I'm going to change this slide
幻灯片要改改了
1 for periodontal disease and 3 for insulin sensitivity and diabetes
牙周病1个,胰岛素敏感症和糖尿病3个
I'm just going to show you a couple of these
我会展示其中一些
but we need to acknowledge that out of that total 30+ studies there are some that are null. There's no doubtabout that
不过我们需要认识到,这30多个研究中毫无疑问,存在一些无效试验
but generally these failed trials either used a dose that was too low or had poor compliance
一般失败的原因是剂量太小或者服从性低
such as in WHI where the compliance is only fifty percent or record where it was only forty percent
比如WHI的服从性就只有百分之四五十
or they failed to achieve a therapeutic blood level or they fail to optimize co-nutrition
或没有达到治疗血液水平,或其它营养素没能优化
I stressed this morning that nutrients work together
早上我就强调过营养素共同作用
They don't work as isolated drugs
它们并非孤立的药物
If you don't optimize the co-nutrient therapy
如果共同作用的营养素无法优化
you're not going to get the benefit of the nutrient you're testing
是无法从测试营养素获益的