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Japanese researchers have developed a groundbreaking drug that can grow teeth, a first in the world, with plans to begin safety trials in September, 2024.
日本研究人员研发出一种突破性的药物，可以让人们长出牙齿，这是世界上首个该类型的药物，并计划于2024年9月开始安全试验。
This innovation was led by a collaboration between industry and academia, including Osaka City Kitano Hospital.
这项创新是由工业界和学术界的合作主导的，其中就包括了大阪市北野医院。
Initial studies on lab rats have shown promising results, indicating the drug's potential to trigger tooth growth by targeting a specific protein, known as USAG1.
在实验室老鼠身上进行的初步研究显示出了令人鼓舞的结果，表明这种药物有可能通过靶向一种名为USAG-1的特定蛋白质来刺激牙齿生长。
In humans, teeth usually stop growing once permanent teeth replaced baby teeth.
就人类而言，一旦恒牙取代了乳牙，那么牙齿就会停止生长。
However, the research team has found that a natural set of third teeth exists, but typically degenerates over time.
不过该研究小组发现，其实存在着一组天然的“第三颗牙齿”，但通常会随着时间的推移而退化。
Their drug works by inhibiting the protein that prevents these third teeth from developing.
研究小组的药物会通过抑制阻止第三颗牙齿发育的蛋白质发挥作用。
The upcoming clinical trials, set to start at Kyoto University Medical School, will first involve adult participants and may later include children.
即将到来的临床试验将在京都大学医学院开始，将首先涉及成人参与者，随后可能包括儿童。
The trials aim to pave the way for commercial availability by 2030.
这些试验旨在为到2030年实现商业化铺平道路。
Currently, about 0.1% of Japanese people are born with significant tooth deficiencies, impacting their ability to eat and speak.
目前，约0.1%的日本人天生就有严重的牙齿缺陷，影响了他们的进食和说话能力。
The new drug could offer a revolutionary alternative to traditional treatments like dentures and implants.
这种新药可能为假牙和种牙等传统治疗方法提供一种革命性的替代方案。
