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But in adolescence this takes another form in terms of the need for individual vigilance
但到了青春期 个人的警觉性又表现出了另一种形式
And it's part of the set of changes and vulnerability sense of it
也就是出现了一系列的变化和脆弱感
that I want to focus on in the final and the rest of this talk
这也是我接下来要讲的主要内容
That is there are profound changes in sleep and circadian regulation
当儿童进入青春期时
at about the time at the onset of puberty
他们的睡眠和作息时间规律发生了深远的变化
This can be a whole talking of itself
对这个问题可以再做一个报告
This elegant work, many colleagues are around the country
全国和全世界有很多出色的研究人员
around the world have been doing work in this area
对这一领域开展了大量的研究
and I'm gonna oversimplify some complicated issues
我打算把一些复杂的问题简化
to highlight the points relevant to this conference
以突出和这个研讨会有关的内容
One thing that happens as kid starts to puberty have this rapid growth is
儿童在进入青春期后 他们发育的速度非常的快
that it actually becomes sleepy err
以至于他们的睡眠出现了错乱
There were responses to not getting enough sleep
他们会对睡眠不足做出反应
and the opportunity to sleep, the capacity to go to sleep
而睡眠机会和睡眠能力则显示出
manifests as Mary Chriskaton
正如玛丽克里斯坎顿很多年前
showed many years ago at Stanford an increased objective sleepiness
在斯坦福的研究结果显示 他们的客观睡眠愿望变得越来越强
There are also some slow wave sleep in REM changes
快速眼动期的脑慢波也发生了改变
that I will talk about in a minute and circadian changes
我一会儿会讲到这个问题 他们的作息时间也发生了变化
It's part of this two-process model
这是一个双过程模型
Process C, the circadian system has set of changes linked to puberty
过程C是作息规律系统 青春期时这一系统发生了一系列的变化
and process S, the homeostatic aspect of sleep pressure system also does
内环境稳态(Process S)是睡眠压力系统的自我平衡 也发生了一系列的变化
What about developmental changes in the sleep-wake homeostasis pressure system?
那么睡眠-苏醒压力系统的自我平衡 发生了哪些和发育有关的变化呢
Again, some really interesting work
人们对此开展了一些有趣的研究
in terms of looking at slow wave stage 3 and 4 sleep deep sleep
关注第3和第4阶段睡眠 以及深度睡眠的慢波变化
the qualitative part that I showed in the earlier studies
我前面给大家看的定量研究
to be relevant to some of the shifts in glucose metabolism
还关注了这几个阶段葡萄糖的代谢情况
and that be measured quantitatively at slow-wave activity
然后对慢波大脑活动情况进行了测量
and this can be looked as sleep propensity toward falling asleep
可以将这个结果视为睡眠倾向 也就是睡着的倾向
I'm just gonna highlight one study
我给大家看一下其中一个研究
